Another vote for the patch.

Knock on wood - I've never been seasick, but I don't want to start.

Started taking some Drammamine when I was doing the 1-day trips out in the Ocean out of Westport. It worked, but made me damn sleepy.

Tried the patch on my last tuna trip. We were out a good 60 miles or so. Worked like a charm and never did get tired, or have any strange side effects.

I did hear that the patch releases enough medicine for an average height/weight human. I have heard that really small and large folks have a hard time with it, as it will either release too much or too little medicine for your body size.

If you're one of these people, ask your doctor about the pill form of what is in the patch. At least at that point, you can the correct dosage for your body size.