B-runs are beasts. Had one pull apart a two-way barrell on me once.

I like 30# Power Pro or 30# Power Pro HiVis (when I can find it) and 12lb UG. Sounds like 10# UG may be better for the water you're fishing as opposed to the 12#.

Have to admit I'm with KD on your question about the 10# UG.

Hold up as a leader material?

Yep, it will just fine.
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On a long enough timeline the survival rate for everyone drops to zero.