If $$ is no object, try one of the Alaska fly-out lodges. Most are limited to a very small number of clients per week. You practically have a plane at your beck and call and you can go practically anywhere you want for a really unique and off the traveled path experience each day you are there - weather permitting. For example, take a look at http://www.alaskarainbowlodge.com. It is probably too late to book this year, but you may be able to plan exactly what you want to do for next year.

If your bones crave something more along the lines of tropical breezes, warm sunsets, cold rum drinks and fine cigars, look into a bonefishing trip. I did this for my 50th. We went to Abaco Island and stayed and fished with Rickmon's Bonefish lodge. We had a spectacular time! If you go, the first thing you should do upon your arrival at the airport is get a Conchburger and a Kalik (or two or three) at the little joint out in back of the airport.