Wheel guns are nice, though also keep an eye out for a Glock 20 (10mm) or 21 (.45acp). The 10mm is like a .40s&w on 'roids, pretty hot cartridge that hits hard, and you get 15+1. The 21 gives you 13+1. If the frame size and grip angle work for your ergonomics, the Glock platform is a great and reliable way to go.