Some good thoughts here, guys. Thanks for the inputs.
A few points to ponder:

Reeling knots in past the top guide might be OK for spinning gear and pulling plugs, but for bait casting reels I'm afraid the potential for backlashes would be great, no?

I've never had issues with tying directly from main line to leader and used to do it regularly using bloodknots without many problems. But that was mono to mono. I bust off a lot of gear and taking excessive time tying new leaders on when a quick trilene knot to a swivel takes care of it doesn't seem practical. (I believe Mooch covers that aspect in #6)

The "Bolo" affect is a great observation, Mooch.

IMO...the clinch knot (improved or not) is neither quicker and definitely not stronger than the trilene knot. (I only wrap the line 3 times, not the recommended 5 or 6, as I find it has less tendency to bind on itself.)

I did ignore the need to use backing, where a splice is definitely necessary, but the strength there is no issue.

I agree that using hi viz and/or fishing ultra clear low water makes long leaders desirable (necessary?). Thanks again.