Lofty,

I shoot pretty much the same set-up as you listed.

I do shoot a lighter bullet (230gr in my memory serves me) and I do shoot 95grs of "Cartridge" powder.

I have shot mine extensively out to 200 yards with no accuracy issues. I am comfortable out to that range, assuming a good rest is available.

When hunting big game, however, I much prefer to shoot at a 125 yards or less.

Gotta love those Remington 700 ML's