I had some major mis-fire issues last Fall w/ my Remington 700.
Found out it was completely caused by not cleaning the bolt assembly as directed in owners manual. I did not have a vice installed on bench at the time of purchase and forgot bolt cleaning entirely until this Fall.

The firing spring in the bolt was crudded up really well and the spring was caked with rust. I soaked the spring in cleaning solvent, cleaned up the bolt assembly really well and polished up the spring w/ steel wool and re-assembled. The spring is much more powerful now.
Have not had an issue yet.

You just gotta clean those Remington's a bit more than the rest, but I love my rifle. Very well balanced.
Just takes awhile to clean back at the house after a day afield.

Really been thinking of getting a Co2 load discharger to avoid the whole cleaning business after a day of hunting (when you don't get a shot at an animal).

My uncle carries the same gun and told me that 90 grains of powder is what that rifle likes. He's a hunter's hunter and toook his advice whole-heartedly. So far, so good.
Just need to get out there more and target shoot more often.

Lofty