If I was making that drive, I'd jump from 90W to 405 north, and then jump on 520 westbound. Take the Montlake exit off 520, and you're just a couple blocks away from UW Med Ctr.

Be advised that I haven't slogged through Seattle in a while.
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She was standin' alone over by the juke box, like she'd something to sell.
I said "baby, what's the goin' price?" She told me to go to hell.

Bon Scott - Shot Down in Flames