I don't floss (except when fly fishing

), and I'm pretty sure that the only reason anyone does is that they have become frustrated with trying to entice fish to strike to a point of deciding that flossing is the only way they will be able to catch fish. I can certainly relate to wanting to catch fish and being frustrated by salmon, so I have some sympathy for the thinking, especially since it's not illegal (or perhaps enforcable) to snag fish in the mouth. That said, flossing (an adaptation of snagging to make it legal) goes against the fundamentals of what I believe (and what most of us learned as kids) to be sport fishing.
More than likely, many (if not all) of you, like me, were introduced to fishing in a lake or stream with trout/bass/panfish/etc. Those to whom that generalization applies likely also used a worm, salmon eggs, or some other sort of thing that mimics fish food to entice the quarry to bite. Eventually, said quarry did bite, making you feel a sense of pride and accomplishment that keeps you going back to the water for more. There are many more reasons why I enjoy fishing, but the chase, the take, the battle, and the release (when required) are what make me choose fishing over other means of enjoying those auxillary benefits. I could still enjoy most of that while flossing, but missing out on the take would leave a pretty big void. Because I personally feel that flossing is unethical (beyond the point to which conventional sport fishing is unethical), it would leave something of a void in my soul as well.
All this said, to each his own....